Analysis of the effect of azithromycin combined with the glucocorticoid for the mycoplasma pneumonia in children / 中国基层医药

ABSTRACT

Objective To investigate the clinical effects of azithromycin combined with glucocorticoid for the mycoplasma pneumonia in children.Methods 124 children with mycoplasma pneumonia were randomly divided into the study group and the control group with 62 cases in each group.On the basis of the routine symptomatic treatment,the control group was given azithromycin(10mg · kg-1 · d-1) and the study group was treated with azithromycin and hydrocortisone sodium succinate (0.2mg/kg) in the first five days,then stop giving hydrocortisone sodium succinate.The total course was two weeks.Results The study group of children with cough,fever and pulmonary rales disappeared significantly shorter than the control group.Comparison of clinical efficacy,the study group effective rate was 95.2％,the control group was 83.9％,the difference was statistically significant (P ＜ 0.05).Study group had 9 cases of adverse reactions,the control group had 14 cases of adverse reactions,the difference was statistically significant (P ＜ 0.05).Conclusion Glucocorticoid combined with azithromycin is used to treat children with mycoplasma pneumoniae pneumonia,which can improve the therapeutic efficacy and shorten treatment time.It is a better choice of clinical treatment for mycoplasma pneumoniae pneumonia in children.