Clinicopathological characteristics and prognosis of ovarian mucinous adenocarcinoma / 肿瘤研究与临床

ABSTRACT

Objective To evaluate the clinicopathological characteristics and prognosis of ovarian mucinous adenocarcinoma.Methods The clinical,pathologic and follow-up data of 39 cases with ovarian mucinous adenocarcinoma were analyzed retrospectively.Results 39 patients with ovarian mucinous adenocarcinoma had a median age of 45 years at diagnosis.The percentage of patients on stage Ⅰ was 59 ％ (23/39),and all patients had the symptoms of ovarian cystic neoplasm or solid mass.There were 24,12,3 cases in grade Ⅰ,Ⅱ,Ⅲ,respectively.Among 15 cases recieved appendectomy,2 cases were appendix infiltrated.The 3-year survival rate of the patients was 63 ％.The result of single-factor analysis showed that the FIGO stage and residual disease after surgery were the correlative factors both in progression free survival (PFS) and overall survival (OS).The result of Cox proportional hazards regression model analysis indicated that residual disease after surgery was the independent prognostic factor of ovarian mucinous adenocarcinoma.Conclusion Ovarian mucinous adenocarcinoma has a better prognosis than other pathological types of ovarian epithelial carcinoma.Appendectomy should be suggested during the surgical treatment of ovarian mucinous adenocarcinoma.The FIGO stage and residual disease after surgery are the important prognostic factors of ovarian mucinous adenocarcinoma.