The influence of PKRP plus titanium laser lithotripsy on PSA and sexual function in prostate hyperplasia patients complicated with bladder stones / 中国基层医药

ABSTRACT

Objective To explore the influence of transurethral plasmakinetic resection of the prostate (PKRP) plus titanium laser lithotripsy on prostate-specific antigen(PSA) and sexual function in prostate hyperplasia patients complicated with bladder stones.Methods 62 patients with prostate hyperplasia and bladder stones were randomly divided into the observation group (n =31 cases) and the control group (n =31 cases).The patients in the observation group were operated through PKRP plus titanium laser lithotripsy,while the patients in the control group were operated through transurethral prostatectomy (TURP) plus pneumatic lithotripsy.Serum PSA was detected before and after operation.Sexual function was evaluated six months after operation.Results The IIEF-5 score in two groups were all decreased after operation.Postoperative IIEF-5 score of the observation group had no significant difference compared with that before operation(t =0.3896,P ＞ 0.05).Postoperative IIEF-5 score of the control group had significant difference compared with that before operation (t =4.2820,P ＜ 0.05).The difference between the two groups was significant (t =3.7473,P ＜ 0.05).Serum PSA in two groups were all significantly decreased 1 month after operation(t =2.0423,15.3077,P ＜ 0.01).It in the observation group was lower than that in the control group(t =13.2142,P ＜ 0.05).Conclusion PKRP plus titanium laser lithotripsy can decrease serum PSA and improve sexual function in prostate hyperplasia patients complicated with bladder stones.