Comparison of the effects of different doses of tramadol in the treatment of patients with postoperative shivering after general anesthesia / 中国基层医药

ABSTRACT

Objective To compare the clinical efficacy and adverse reactions of different doses of tramadol in the treatment of patients with postoperative shivering after general anesthesia and to explore the appropriate dose of tramadol for the treatment of general anesthesia shivering.Methods 87 cases who required elective general anesthesia in patients with abdominal surgery were selected in our hospital.They were divided into five groups according to the wishes of patients.Among them,17 patients of the control group did not receive tramadol.17 patients of the observation group one were given intravenous tramadol 0.5mg/kg.17 patients of the observation group two were givenintravenous tramadol 1.0mg/kg.18 patients of the observation group three were given intravenous tramadol 1.5mg/kg and 18 patients of the observation group four were given intravenous tramadol 2.0mg/kg.After treatment,the degree of chills of the patients was evaluated.The difference of the chills score of five groups was observed before and after treatment.The clinical efficacy and adverse reactions of different doses of tramadol were compared.Results Tramadol could significantly reduce the shivering score and improve the efficacy.The incidence rate of adverse reactions was 0.00％,0.00％,0.00％,5.56％,61.11％,and the total effective rate was 11.76％,70.59％,100.00％,94.44％,77.78％ in five groups.The clinical efficacy of the observation group two were significantly better than the other groups,the difference was statistically significant (x2 =9.85,P ＜ 0.05).Conclusion Tramadol at the dose of 1.0mg/kg or 1.5mg/kg can not only significantly improve the clinical efficacy of postoperative shivering,but also can reduce the incidence rate of adverse reactions.It is the optimal dose for clinical treatment,which is worthy of clinical application.