Prognosis of breast conservation therapy in young woman breast carcinoma / 中华普通外科杂志
Chinese Journal of General Surgery
;
(12): 593-596, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-436999
ABSTRACT
Objective To identify the clinical characteristics and prognostic factors in young women of breast cancer treated with breast conservation therapy.Methods Clinical data of 605 cases of breast cancer patients undergoing breast conserving therapy were reviewed in our hospital from Jan 1998 to July 2008.According to their age,these patients were divided into young group (age≤ 35 years,n =110 cases) and the elderly group (age > 35 years,n =495 cases).Survival factors were analyzed by Cox proportional hazards regression model.Results During the median follow-up of 61 months,the 5-year local-regional relapse-free survival was 92.6% and 96.8%,respectively (P =0.074) ; the 5-year distant metastasis-free survival and overall survival between the two groups were (89.7% vs.95.2%,P =0.001)and (96.4% vs.98.9%,P =0.046).Multivariate analysis revealed that lymph node metastasis and adjuvant radiotherapy were independent risk factors for local-regional relapse.Distant metastasis and overall survival were determined by lymph node metastasis,adjuvant radiotherapy and age.Conclusions Age is not an independent factors affecting tumor local recurrence in Chinese young female patients of early breast cancer receiving breast conserving surgical therapy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
Chinese Journal of General Surgery
Year:
2013
Type:
Article
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