Comparison of different doses of sufentanil and ropivacaine in epidural anesthesia for labor analgesia / 中国基层医药

ABSTRACT

Objective To analyze the effect of different doses of sufentanil combined with ropivacaine in labor analgesia and its adverse events.Methods According to the digital table,90 vaginal delivery women were randomly divided into group A,groupB and group C,each group 30 cases,which all used epidural anesthesia.Group A chosen 0.5％ ropivacaine 20ml,and group B chosen 0.5％ ropivacaine tetracaine 20ml + sufentanil 5μg,and group C used 0.5％ ropivacaine 20ml + sufentanil 10μg.The visual analogue score(VAS),modified Bromage score,incidence of adverse reactions of pregnant women at different time points were compared.Results (1) At 10min,60min after medication and the cervix openning whole,the VAS scores of pregnant women in group B were significantly lower than those in group A(t =5.5089,5.9342,4.2642,all P ＜0.05),and at 10min,60min after medication,the cervix openning whole and at 1 h after medication,the VAS scores of pregnant women in group C were significantly lower than those in group A (t =13.9558,6.7654,5.2154,all P ＜ 0.05).Compared with group B,the VAS scores of pregnant women in group C at 10 min and 60 min after medication were significantly lower(t =7.4353,4.2165,3.6865,all P＜0.05).(2)The itching rate in group C (26.67％) was significantly higher than that in group B(3.33％) and group A (0) (χ2 =4.7059,7.0673,all P ＜ 0.05).Conclusion In epidural analgesia,5 μg sufentanil + 0.5 ％ ropivacaine 20ml analgesic has good effect and less adverse reactions,which can be used widely.