Analysis of relative risk factors of patients with diabetic foot ulcer combined with peripheral arterial disease / 中国医师进修杂志

ABSTRACT

Objective To investigate the clinical characteristics and risk factors of peripheral arterial disease(PAD)in patients with diabetic foot ulcer(DFU).Methods Two hundred and eleven hospital patients with DFU were enrolled and divided into is chemic ulcer (IU) group (136 patients,with PAD) and non-IU group(75 patients,without PAD).The clinical characteristics were retrospectively analyzed.Results Single factor analysis showed that age,the course of diabetes mellitus,smoking,accompanied with coronary artery disease,the course of DFU,triacylglycerol,low-density lipoprotein cholesterol,fasting plasma glucose (FPG),post-prandial 2 h blood glucose,apaprotein(Apo)A1 and ApoB,glycosylated hemoglobin (HbA1c),systolic blood pressure,C-reactive protein were risk factors (P ＜0.01 or ＜0.05).Multiple factors Logistic regression showed that age(OR =0.983,P =0.006),accompanied with coronary artery disease(OR =4.800,P=0.001),FPG (OR =1.153,P=0.001),HbA1c (OR =0.798,P=0.001) were important risk factors of DFU.Conclusions The degree of lesion in DFU combined with PAD is more seriously and associated disease are more.Age,accompanied with coronary artery disease,FPG,HbA1c are the important risk factors of DFU combined with PAD.