Analysis on the influencing factors on the effect of antipsychotic towards schizophrenia / 重庆医学

ABSTRACT

Objective To analyze the influencing factors on the effect of antipsychotics towards schizophrenia by logistic regres-sion analysis .Methods The effects of 146 cases of schizophrenia treated with antipsychotic before and after the treatment were an-alyzed ,and the logistic regression analysis was employed to explore the influencing factors .Results The symptom score after antip-sychotic treatment were superior to that before treatment .Logistic regression analysis indicated that the influencing factors were smoking ,history ,diabetes ,duration ,nationality ,type of first onset ,nAchR (rs 1355920) and DISCl (rs 821597) .Conclusion Many factors influence the effect of antipsychotic ,and treatment program should be developed according to the specific circumstances of the patients .