Roles of hypoxia and Notch1 in multiple myeloma / 国际肿瘤学杂志
Journal of International Oncology
;
(12): 542-546, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-438949
ABSTRACT
Recently numerous studies have demonstrated that Notch signaling pathway plays a critical role in regulating cell proliferation and differentiation in hematopoietic microenvironment,which is associated with MM occurrence and the drug resistance.The latest researches show that there are close relations between hypoxia and Notch signaling pathway in tumor occurrence and progression.Exploring the interactions of microenvironment of hypoxia,HIF-1α and Notch signaling pathway will provide theoretical basis for MM targeted therapy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of International Oncology
Year:
2013
Type:
Article
Similar
MEDLINE
...
LILACS
LIS