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Surveillance of bacterial antibiotic resistance in traumatic wound infection: a report of 1006 cases / 中华创伤杂志
Chinese Journal of Trauma ; (12): 1094-1098, 2013.
Article in Chinese | WPRIM | ID: wpr-439202
ABSTRACT
Objective To monitor the distribution of pathogenic bacteria causing wound infection in trauma patients and their susceptibility to antibiotics in an effort to offer evidence for the rational clinical use of antibiotics.Methods Pathogens were identified by expressive type,but a very few was determined by the molecular methods.Micro-dilution or Kirby-Bauer method for minimum inhibitory concentration (MIC) was adopted for drug susceptibility test.Results A total of 121 species of pathogens numbering 1,257 bacterial strains were isolated from 1,066 patients.Strain number of the top 10 species accounted for 70.09%.Gram-positive cocci accounted for 48.93% and Gram-negative bacilli for 49.72%.Among Staphylococcus aureus and epidermidis,methicillin-resistant bacterial strains accounted for 34.76% and 71.08% respectively,but none were resistant to vancomycin or linezolid.Enterococcus faecalis contained 6.06% vancomycin-resistant enterococcal (VRE) and remained > 90% sensitive to teicoplanin,ampicilin and vancomycin.Enterococcus faecium contained 10.53% VRE and remained >90% sensitive to teicoplanin and > 80% sensitive to vancomycin.Baumanii contained 12.77% multidrug resistant strains and remained > 70% sensitive to imipenem and meropenem.Baumanii/calcoaceticus complex contained 29.72% multi-drug resistant strains and remained > 50% sensitive to imipenem and meropenem.Pseudomonas aeruginosa contained 3.73% multi-drug resistant strains and remained >90% sensitive to amikacin,meropenem,imipenem and piperacillin/tazobactam.No E.coli,klebsiella pneumoniae and enterobacter cloacae resistant to imipenem or meropenem were found.E.coli contained 69.51% extended-spectrum β-lactamases (ESBLs)-producing strains and remained > 90% sensitive to piperacillin/tazobactam and > 80% sensitive to amikacin.Klebsiella pneumoniae contained 53.13% ESBLs-producing strains and remained > 80% sensitive to amikacin.Conclusions Common bacteria are the leading cause of posttraumatic infection.Enterococcus faecalis and enterococcus faecium demonstrate higher susceptibility to teicoplanin; two kinds of acinetobacter demonstrate higher susceptibility to imipenem.

Full text: Available Index: WPRIM (Western Pacific) Type of study: Screening study Language: Chinese Journal: Chinese Journal of Trauma Year: 2013 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Type of study: Screening study Language: Chinese Journal: Chinese Journal of Trauma Year: 2013 Type: Article