Risk factors for early rebleeding after elective endoscopic variceal ligation(EVL) and long-term outcome: a retrospective analysis / 中华消化内镜杂志
Chinese Journal of Digestive Endoscopy
;
(12): 668-670, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-439406
ABSTRACT
Objective To evaluate the risk factors for early rebleeding (ERB) after elective endoscopic variceal ligation (EVL) in cirrhotic patients and the influence of ERB on the long-term survival.Methods A total of 198 cirrhotic patients who received elective EVL were retrospectively evaluated.Twenty-six patients rebleeded within 6 weeks after initial EVL and were assigned to the ERB group.One hundred and seventy-two other cirrhotic patients were assigned to the control group.Multivariate analysis was used to define the high risk factors of ERB.A Kaplan-Meier analysis was performed to evaluate the cumulative survival rates between two groups.Results The Child-Pugh classification (P =0.016),Child-Pugh scores (P=0.012),and the total bilirubin (P =0.001) were significantly different between ERB and control group.Multivariate analysis showed total bilirubin was the only independent risk factor of ERB (OR =2.02,95%CI1.04-4.04,P =0.008).The proportional mortality indicator of bleeding-related deaths was 66.7% (10/15) in ERB group and 13.6% (6/44) in control group (P <0.01).The five-year curmulative survival rate of the control-group was significantly higher than that of the rebleeding group (67.8% vs.25.3%,P < 0.01).Conclusion Cirrhotic patients with ERB after elective EVL have a poor prognosis.High level of total bilirubin may predict ERB.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Etiology study
/
Prognostic study
/
Risk factors
Language:
Chinese
Journal:
Chinese Journal of Digestive Endoscopy
Year:
2013
Type:
Article
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