Pathogens distribution and drug resistance analysis in patients with stroke-associated pneumonia / 中国医师进修杂志

ABSTRACT

Objective To analyze the pathogens distribution and drug resistance in acute stroke with stroke associated pneumonia (SAP) patients,and provide references for proper clinical application of antibiotics.Methods A retrospective investigation was performed to analyze the pathogens and the drug resistance of 131 acute stroke with SAP patients.Results Among 148 strains of isolated pathogens,the Gram-negative bacteria accounted for 66.22％ (98/148),including Klebsiella pneumoniae,Pseudomonas aeruginosa,Escherichia coli,Acinetobacter baumannii,Enterobacter cloacae and so on.Gram-positive bacteria accounted for 26.35％ (38/148).Staphylococcus aureus ranked the first,followed by Coagulase negative staphylococcus and Enterococcus faecalis.Fungi accounted for 7.43％ (12/148),mainly including Candida albicans.They had varying degrees of resistance to commonly used antibiotics.Conclusions Gram-negative bacteria are predominant in SAP.Drug resistance is very serious,and the antibiotics should be selected in clinic according to the result of drug susceptibility test.