Microglial Toll-like receptor 2 and cerebral ischemia / 国际脑血管病杂志
International Journal of Cerebrovascular Diseases
;
(12): 792-795, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-440239
ABSTRACT
Microglia can be activated immediately after acute cerebral ischemia and play a role of double-edged sword of nerve repair and neurotoxicity.Studies in recent years have suggested that this dual role of microglia can be achieved by a Toll-like receptor 2 (TLR2) signal transduction pathway.Therefore,reasonable regulation of TLR2 expression of microglia may improve the therapeutic effect of cerebral ischemia to a certain extent.This article reviews the mechanisms of TLR2 in cerebral ischemia and the possible interventions.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
International Journal of Cerebrovascular Diseases
Year:
2013
Type:
Article
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