Reserch progress of nasopharyngeal carcinoma related gene / 国际肿瘤学杂志
Journal of International Oncology
; (12): 662-665, 2013.
Article
in Zh
| WPRIM
| ID: wpr-440431
Responsible library:
WPRO
ABSTRACT
The occurrence of nasopharyngeal carcinoma is a multi-gene,multi-step process.Among them,oncogene activation and antioncogene inactivation is the important mechanism.The related oncogenes of nasopharyngeal carcinoma contain Bcl-2,hepatocyte growth factor (HGF),cyclooxygenase-2 (COX-2) and latent membrane protein-1 (LMP-1).The related antioncogenes of nasopharyngeal carcinoma contain p53,p16,Nm23-H1 and PTEN.With the deepening research on genes,studies also find that nasopharyngeal carcinoma is related to PECAM-1,MMP-9 and RECK.These genes play important roles in the occurrence and development of nasopharyngeal carcinoma,which may become new targets for the treatment of nasopharyngeal carcinoma.
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Language:
Zh
Journal:
Journal of International Oncology
Year:
2013
Type:
Article