Role of centrosome in tumorigenesis and oncotherapy / 基础医学与临床
Basic & Clinical Medicine
;
(12): 431-433, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-440608
ABSTRACT
The centrosome plays a crucial role in the maintaining of cell conformation,mitosis and chromosome seg-regation.It responds to the DNA damage and keeps the genome stability via cross-talking with the intranuclear DNA damage repair system.The apoptosis of tumor cells can be induced through inhibition of the duplication of centro-some.So the inhibitors of centrosomal proteins will be a potential anti-tumor therapy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Basic & Clinical Medicine
Year:
2010
Type:
Article
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