F-18 Sodium Fluoride Positron Emission Tomography/Computed Tomography for Detection of Thyroid Cancer Bone Metastasis Compared with Bone Scintigraphy
Korean Journal of Radiology
;
: 281-288, 2016.
Article
in English
| WPRIM
| ID: wpr-44147
ABSTRACT
OBJECTIVE:
The aim of the study was to compare the diagnostic performances of F-18 sodium fluoride positron emission tomography/computed tomography (bone PET/CT) and bone scintigraphy (BS) for the detection of thyroid cancer bone metastasis. MATERIALS ANDMETHODS:
We retrospectively enrolled 6 thyroid cancer patients (age = 44.7 ± 9.8 years, MF = 15, papillaryfollicular = 24) with suspected bone metastatic lesions in the whole body iodine scintigraphy or BS, who subsequently underwent bone PET/CT. Pathologic diagnosis was conducted for 4 lesions of 4 patients.RESULTS:
Of the 17 suspected bone lesions, 10 were metastatic and 7 benign. Compared to BS, bone PET/CT exhibited superior sensitivity (10/10 = 100% vs. 2/10 = 20%, p = 0.008), and accuracy (14/17 = 82.4% vs. 7/17 = 41.2%, p 0.05).CONCLUSION:
Bone PET/CT may be more sensitive and accurate than BS for the detection of thyroid cancer bone metastasis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Sodium Fluoride
/
Bone and Bones
/
Bone Neoplasms
/
Thyroid Neoplasms
/
Fluorine Radioisotopes
/
Tomography, X-Ray Computed
/
Retrospective Studies
/
Contrast Media
/
Positron-Emission Tomography
/
Whole Body Imaging
Type of study:
Diagnostic study
/
Observational study
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
English
Journal:
Korean Journal of Radiology
Year:
2016
Type:
Article
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