The Expression of MCP-1 in the Diabetes Mellitus Skin Defect Healing / 昆明医科大学学报
Journal of Kunming Medical University
;
(12): 51-54, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-441563
ABSTRACT
Objective To study the expression of MCP-1 in the diabetes mellitus skin defect healing, then discuss its effect. Methods The diabetes mellitus models were established, and the expression of MCP-1 was detected by immunohistochemical staining and Elisa. Results The immunohistochemistry stain showed that the expression of MCP-1 in DM group was higher than that in control group at all time. And the serum value of MCP-1 in DM group had statistical significance ( <0.05) at 3 days or 1 week, but that in 2 weeks and 4 weeks was no statistical significance ( <0.05) . Conclusion The MCP-1 might play a role in the healing of diabetes mellitus skin defect through mediate abnormal inflammatory response.
Full text:
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Kunming Medical University
Year:
2013
Type:
Article
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