Research progress of microRNA related to the relapse and metastasis of postoperative lung cancer / 肿瘤研究与临床

ABSTRACT

microRNAs (miRNAs) related to the recurrence and metastasis of non-small-cell lung cancer (NSCLC) in recent years have made important progress.The authors search the clinical researches related to the link between the miRNA and the recurrence and metastasis of postoperative NSCLC on PubMed.The clinical studies produced contradictory data.miRNA differentially expressed in lung cancer based on their data.Some but not all suggested that the miRNA is associated with the metastasis and recurrence of NSCLC,suggesting the miRNA could be a potential therapeutic targets for therapy of lung cancers.However,most studies are still at the screening stage,which is lack of a large group of patients,especially in random,controlled study to verify the miRNA predict recurrence transfer orientation or prognosis,which can be the direction for the practice of clinical trials in the future.