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Clinical value of pulmonary embolism severity index in non high-risk acute pulmonary thromboembolism / 中国医师进修杂志
Chinese Journal of Postgraduates of Medicine ; (36): 18-21, 2013.
Article in Chinese | WPRIM | ID: wpr-442451
ABSTRACT
Objective To evaluate the clinical value of pulmonary embolism severity index (PESI) in non high-risk acute pulmonary thromboembolism (APTE) patients treated with sequential anticoagulation.Methods Non high-risk APTE patients treated with sequential anticoagulation were divided into two groups according to PESIhigh-value group and low-value group.Prognosis and treatment response was compared between two groups.Results There were 82 cases in high-value group,and 76 cases in low-value group.The rate of adverse events in high-value group was significantly higher than that in low-value group [23.2%(19/82) vs.7.9% (6/76)] (x2 =5.0698,P =0.009),and 30 days cumulative hazard was also significantly higher than that in low-value group (P < 0.05).The sensitivity of predicting adverse events by PESI was 76.0%,specificity was 52.6%,positive predicting value was 64.6%,and negative predicting value was 65.9%.The mortality in high-value group was significantly higher than that in low-value group [9.8%(8/82) vs.1.3% (1/76)] (P =0.022).After 30 days of anticoagulation,the pulmonary artery systolic pressure,internal diameter of right ventricle in high-value group was significantly higher than that in low-value group [(39.4 ± 8.1) mm Hg (1 mm Hg =0.133 kPa) vs.(27.2 ± 5.5) mm Hg,(33.0 ± 7.8) mm vs.(21.7 ± 4.6) mm] (P =0.034,0.021),and arterial oxygen partial pressure was significantly lower than that in low-value group[(75.15 ± 12.41) mm Hg vs.(86.36 ± 9.22) mm Hg](P=0.016).Conclusions PESI can effectively predict short-term prognosis of non high-risk APTE patients treated with sequential anticoagulation.At least some of these patients might need treatment other than sequential anticoagulation.

Full text: Available Index: WPRIM (Western Pacific) Type of study: Etiology study / Prognostic study Language: Chinese Journal: Chinese Journal of Postgraduates of Medicine Year: 2013 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Type of study: Etiology study / Prognostic study Language: Chinese Journal: Chinese Journal of Postgraduates of Medicine Year: 2013 Type: Article