Influence of nutrition support therapy on quality of life in patients with advanced tumors / 中国基层医药

ABSTRACT

Objective To investigate the effect of nutrition support therapy on quality of life in patients with advanced tumors.Methods 70 patients with advanced tumors were randomly divided into the observation group and the control group,each group had 35 cases.The control group was given conservative treatment,together with the ordinary liquid,semi-liquid or diet.The observation group was given nutrition support therapy on the basis of conservative therapy.The nutrition and immune index and symptom score,quality of life were compared between the two groups.Results The nutrition,immune indexes (Alb,BMI and NK) and symptom score (malaise,anorexia,insomnia,pain) of the observation group were significantly improved(t =7.92,6.98,5.56,7.41,6.47,5.61,4.52,all P ＜ 0.05),which were significantly better than those of the control group(t =4.42,4.10,4.03,6.42,5.60,4.83,4.23,all P ＜0.05).The physical function,role function,emotional function,cognitive function score and total score of the observation group were significantly higher than those of the control group,the differences were statistically significant (t =8.12,6.08,5.12,4.78,4.32,all P ＜ 0.05).Conclusion Nutrition support therapy can improve the nutritional status of cancer patients in advanced stage,relieve symptoms,improve immune function and quality of life,which is worthy of clinical application.