Evaluating the Utility of Rapid Point-of-Care Potassium Testing for the Early Identification of Hyperkalemia in Patients with Chronic Kidney Disease in the Emergency Department
Yonsei Medical Journal
;
: 1348-1353, 2014.
Article
in English
| WPRIM
| ID: wpr-44331
ABSTRACT
PURPOSE:
Severe hyperkalemia leads to significant morbidity and mortality if it is not immediately recognized and treated. The concentration of potassium (K+) in the serum increases along with deteriorating renal function. The use of point-of-care K+ (POC-K+) in chronic kidney disease (CKD) could reduce the time for an accurate diagnosis and treatment, saving lives. We hypothesized that POC-K+ would accurately report K+ serum level without significant differences compared to reference testing, regardless of the renal function of the patient. MATERIALS ANDMETHODS:
The retrospective study was performed between January 2008 and September 2011 at an urban hospital in Seoul. The screening program using POC was conducted as a critical pathway for rapid evaluation and treatment of hyperkalemia since 2008. When a patient with CKD had at least one warning symptom or sign of hyperkalemia, both POC-K+ and routine laboratory tests were simultaneously ordered. The reliability of the two assays for serum-creatinine was assessed by intra-class correlation coefficient (ICC) analysis using absolute agreement of two-way mixed model.RESULTS:
High levels of reliability were found between POC and the laboratory reference tests for K+ (ICC=0.913, 95% CI 0.903-0.922) and between two tests for K+ according to changes in the serum-creatinine levels in CKD patients.CONCLUSION:
The results of POC-K+ correlate well with values obtained from reference laboratory tests and coincide with changes in serum-creatinine of patients with CKD.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Potassium
/
Blood Chemical Analysis
/
Reproducibility of Results
/
Retrospective Studies
/
Sensitivity and Specificity
/
Point-of-Care Systems
/
Emergency Service, Hospital
/
Renal Insufficiency, Chronic
/
Hyperkalemia
Type of study:
Diagnostic study
/
Practice guideline
/
Observational study
/
Prognostic study
Limits:
Humans
Language:
English
Journal:
Yonsei Medical Journal
Year:
2014
Type:
Article
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