Expression of Gult-1 in cervical adenocarcinoma and its significance / 肿瘤研究与临床
Cancer Research and Clinic
;
(6): 39-41, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-443523
ABSTRACT
Objective To study the expression of Gult-1 in cervical adenocarcinoma and prognosis analysis.Methods Gult-1 was detected by immunohistochemistry (EnVision) in cervical adenocarcinoma and cancer adjacent tissue.Results In cancer adjacent tissue and cervical adenocarcinoma,the positive rates of Gult-1 were 2.22 % (1/45),58.67 % (44/75),respectively,and there was statistical significance between them (x2 =38.23,P =0.00).The expression of Gult-1 was not correlated to age,histological classification and infiltrated depth (all P > 0.05).However,it was correlated to tumor size,histological grade and lymphatic nodes metastasis (all P < 0.05).The survival rate of positive Gult-1 patients was lower than negative Gult-1 patients (x 2 =4.27,P =0.04).Conclusion The over-expression of Guh-1 in cervical adenocarcinoma indicates poorly differentiated cancer,the possibility of lymphatic nodes metastasis and unfavourable prognosis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Cancer Research and Clinic
Year:
2014
Type:
Article
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