Protective roles of lipoxin A4 in cerebral ischemia-reperfusion / 国际脑血管病杂志
International Journal of Cerebrovascular Diseases
;
(12): 67-71, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-444666
ABSTRACT
Lipoxin A4 is an arachidonic acid metabolite,it is an important endogenous anti-inflammatory mediators in the body,which is known as an inflammatory braking signal. Inflammatory response is an important factor for causing cerebral ischemia-reperfusion injury.Lipoxin A4 can exert neuroprotective effects by inhibiting inflammatory response.In addition,lipoxin A4 can also reduce blood-brain barrier permeability,reduce cerebral edema,and promote recovery of neurological function.This article reviews the neuroprotective roles and mechanisms of lipoxin A4 in cerebral ischemia-reperfusion.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
International Journal of Cerebrovascular Diseases
Year:
2014
Type:
Article
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