Analysis of clinical feature and misdiagnosis of pulmonary granulomatosis with polyangitis / 中国医师进修杂志
Chinese Journal of Postgraduates of Medicine
;
(36): 20-22, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-445120
ABSTRACT
Objective To summarize and evaluate the clinical feature and misdiagnosis of pulmonary granulomatosis with polyangitis (GPA).Methods The clinical data of 47 patients of pulmonary GPA were analyzed retrospectively.The clinical feature and misdiagnosis were summarized.Results These patients were most commonly misdiagnosed as pulmonary infectious disease (61.8%,34/55) and pulmonary malignancy (27.3%,15/55) was the next in line.70.2%(33/47) patients had nose and sinus involvement,40.4%(19/47) patients had kidney involvement,25.5% (12/47) patients had rash,19.1%(9/47) patients had eyes involvement,6.4% (3/47) patients had peripheral neuritis,6.4% (3/47) patients had gastrointestinal bleeding,4.3%(2/47) patients had pericardial effusion,87.2%(41/47) patients had positive for antineutrophil cytoplasmic(cANCA),76.6%(36/47) patients had positive for proteinase-3.Conclusions Almost all pulmonary GPA patients have extra-pulmonary multi-systemic involvement.They are often misdiagnosed as pulmonary infectious diseases and malignancy.Educating doctors on GPA constantly and screening possible patients with cANCA testing may help reduce the misdiagnosis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Postgraduates of Medicine
Year:
2014
Type:
Article
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