Impact of Multivessel Coronary Disease With Chronic Total Occlusion on One-Year Mortality in Patients With Acute Myocardial Infarction
Korean Circulation Journal
;
: 95-99, 2012.
Article
in English
| WPRIM
| ID: wpr-44514
ABSTRACT
BACKGROUND AND OBJECTIVES:
The impact of multivessel coronary disease (MVD) with chronic total occlusion (CTO) on one-year mortality in patients with acute myocardial infarction (AMI) is not clearly known. We investigated the impact of MVD with concurrent CTO lesion on one-year mortality in patients with AMI. SUBJECTS ANDMETHODS:
We studied 1008 consecutive patients who underwent coronary angiography between November 2005 and December 2008 with a diagnosis of AMI.RESULTS:
Among 1008 patients, 432 patients (43%) had MVD, and 88 patients (8.7%) had CTO lesion. The one-year overall mortality was higher in patients with MVD than in patients with single vessel disease (SVD) (10.2% vs. 5.9%, p=0.012). However, the one-year overall mortality was not significantly higher in patients with CTO lesion than in patients without that lesion (12.5% vs. 7.3%, p=0.080). In multivariate analysis, independent predictors of one-year overall mortality were age older than 65 years {hazard ratio (HR) 2.41, 95% confidence interval (CI) 1.43 to 4.08}, Killip class > or =III (HR 3.59, 95% CI 2.24 to 5.77), ST-elevation myocardial infarction (HR 2.45, 95% CI 1.49 to 4.05) and MVD (HR 1.76, 95% CI 1.07 to 2.89).CONCLUSION:
Patients with MVD showed higher one-year mortality than patients with SVD. However, the presence of CTO was not an independent predictor of one-year mortality in this study that included patients with successfully revascularized CTO lesion.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prognosis
/
Chronic Disease
/
Multivariate Analysis
/
Coronary Angiography
/
Coronary Disease
/
Coronary Occlusion
/
Glycosaminoglycans
/
Myocardial Infarction
Type of study:
Prognostic study
Limits:
Humans
Language:
English
Journal:
Korean Circulation Journal
Year:
2012
Type:
Article
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