The influence of shenmai injection on CRP and Hcy of patients with non-ST-segment elevation acute coronary syndrome / 中国基层医药

ABSTRACT

Objective To explore the influence of shenmai injection on C-reactive protein(CRP) and homocysteine(Hcy) of patients with non-ST-segment elevation acute coronary syndrome.Methods 96 patients with nonST-segment elevation acute coronary syndrome were randomly divided into the control group(48 cases) and the observation group(48 cases).The patients in the control group were treated through the conventional treatment,while the patients in the treatment group were treated by shenmai injection based on the conventional therapy.They were all treated for 14 days.CRP and Hcy were detected before and after treatment.Results The total effective rate of the observation group was 95.8％,which was significantly higher than 87.5％ of the control group (x2 =4.760,P ＜0.05).The plasma levels of CRP and Hcy were all decreased after treatment in both two groups.The CRP and Hcy in the observation group were significantly lower than those in the control group (t =2.927,2.624,all P ＜ 0.05).Conclusion Shenmai injection can significandy decrease the plasma levels of CRP and Hcy in patients with non-ST-segment elevation acute coronary syndrome.