Improvement in Life Quality of Postmenopausal Women with Breast Cancer Operation by Zoledronic Acid and Letrozole / 中国药师
China Pharmacist
;
(12): 801-804, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-445971
ABSTRACT
Objective:
To study the treatment effect of zoledronic acid and letrozole on life quality of postmenopausal women with breast cancer operation.Methods:
Totally 26 patients were in the control group,and given letrozole,and 23 patients were in the treat-ment group with zoledronic and letrozole. The patients in the two groups were assessed bone mineral density ( BMD) of hip and lumbar vertebrate before the treatment and the 6th and 12th month after the treatment. BALP, CTX, VAS, FACT-B and adverse reactions were also assessed at the 6th and 12th month after the treatment.Results:
Improvement of BMD and FACT-B in the treatment group was sig-nificantly better than that in the control group. BALP, CTX and VAS in the treatment group were all decreased more significantly than those in the control group (P0. 05).Conclusion:
By preventing bone loss and increasing BMD, the combination of zoledronic acid and letrozole can effectively im-prove the life quality of postmenopausal women with breast cancer operation.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacist
Year:
2014
Type:
Article
Similar
MEDLINE
...
LILACS
LIS