Therapeutic Effect and Safety of Repaglinide and Gliclazide in the Treatment of Elderly Type 2 Diabetes Mellitus / 中国药师
China Pharmacist
;
(12): 808-810, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-445982
ABSTRACT
Objective:
To evaluate the clinical efficacy and safety of repaglinide and gliclazide in the treatment of elderly type 2 di-abetes mellitus (T2DM).Methods:
A total of 225 T2DM patients with the age over 60 were enrolled and randomly divided into repa-glinide group (n=112) and gliclazide group (n=113). The repaglinide group was given repaglinide 0. 5~2 mg, po, tid, while the gliclazide group was given gliclazide modified release tablets 30~120 mg, po, qd,both with the treatment course of 12 weeks. The level of FPG, 2h PG, HbAlC, TC and TG and the side effects were observed and the clinical efficacy was compared between the two groups.Results:
The level of FPG, 2h PG, HbAlc and TC in the two groups showed significant decrease after the treatment (P0. 05).Conclusion:
Both repaglinide and gliclazide show safe and reliable efficacy in the treatment of elderly T2DM.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacist
Year:
2014
Type:
Article
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