Influence of geniposide on collagen II synthesis of cultured chondrocytes in vitro / 中国组织工程研究
Chinese Journal of Tissue Engineering Research
;
(53): 3149-3152, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-446608
ABSTRACT
BACKGROUND:
Chinese herb Cape Jasmine Fruit can activate the chondrocytes and geniposide is an important component in this herb.OBJECTIVE:
To investigate the effect of geniposide on col agen II synthesis in rat chondrocytes cultured in vitro.METHODS:
Rat chondrocytes were separated and cultured in vitro. The chondrocytes were then interfered with 25, 50 and 100 mmol/L geniposide. Normal control group was also set. Col agen II mRNA and protein expression was detected with semi-quantitative RT-PCR and western blot analysis, respectively. RESULTS ANDCONCLUSION:
RT-PCR and western blot analysis results showed that, geniposide at 25, 50 and 100 mmol/L increased the col agen II mRNA and protein expression (P<0.01). Geniposide can promote the synthesis of col agen II in rat chondrocytes cultured in vitro.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Tissue Engineering Research
Year:
2014
Type:
Article
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