Three Cases Showing Combined Features of Syringocystadenoma Papilliferum andTubular Apocrine Adenoma Superimposed on Nevus Sebaceus / 대한피부과학회지

ABSTRACT

Both syringocystadenoma papilliferum and tubular apocrine adenoma are benign skin appendage tumors of apocrine differentiation. They may be isolated and easily discernible, but in some cases, it is difficult to differentiate them into separate entities or diseases with overlapping features. We herein report three cases showing features of both syringocystadenoma papilliferum and tubular apocrine adenoma simultaneously. They presented as a 20-year-old woman with linear verrucous erythematous plaque with grouped papules on the left sideburn area, a 64-year-old man with verrucous plaque on the right temporal scalp, a 48-year-old man with verrucous erythematous patch on the occipital scalp and commonly showed syringocystadenoma and tubular apocrine adenoma. All cases had been present since birth and also showed similar histopathologic features as follows; occasional fetal hair germ-like immature pilosebaceous structures or somewhat hypertrophied sebaceous glands directly connecting to surface epidermis, suggesting the association with nevus sebaceus in a variable degree.