Relationship between polymorphism of COX-2 and susceptibility of bladder cancer / 实用医学杂志
The Journal of Practical Medicine
;
(24): 1076-1079, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-448232
ABSTRACT
Objective To investigate the correlation of polymorphism of 8473 (T/C,rs5275) in the 3′-untranslated region of cyclooxygenase-2 (COX-2) gene with bladder cancer. Methods A case-control study on the relation between COX-2 polymorphism and bladder cancer was performed in this study. The Taqman SNP genotyping assay was used to study the COX-2 rs5275 polymorphism. Results The differences in allele or genotype distributions of COX-2 rs5275 between cases and controls (all P 0.05). Conlusion The separate effect of rs5275 polymorphism of COX-2 is associated with the susceptibility of bladder cancer, the TC/CC genotypes may be a protective factor.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Observational study
Language:
Chinese
Journal:
The Journal of Practical Medicine
Year:
2014
Type:
Article
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