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Diagnostic value of assay of brain natriuretic peptide in patients with sepsis of blood-stasis syndrome / 中西医结合学报
Journal of Integrative Medicine ; (12): 266-9, 2008.
Article in Chinese | WPRIM | ID: wpr-449194
ABSTRACT

OBJECTIVE:

To explore the diagnostic value of brain natriuretic peptide (BNP) level in patients with sepsis of blood-stasis syndrome.

METHODS:

The prospective method of clinical diagnostic test and evaluation principles of diagnostic test were applied. One hundred and seventy-four patients with sepsis were divided into two groups blood-stasis syndrome group and non blood-stasis syndrome group. The levels of serum BNP in two groups were detected.

RESULTS:

The level of BNP in sepsis patients was related to blood-stasis syndrome (P<0.01). BNP cut-off level was 150 ng/L, sensitivity was 85.3%, specificity was 81%, the maximum value of Youden index was 0.663, and the area under the receiver operating characteristic curve (ROC) value was (0.886+/-0.025).

CONCLUSION:

BNP can be used as an objective index of blood-stasis syndrome diagnosis for sepsis, and BNP with boundary value of 150 ng/L is an optimal biological index.
Full text: Available Index: WPRIM (Western Pacific) Type of study: Diagnostic study Language: Chinese Journal: Journal of Integrative Medicine Year: 2008 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Type of study: Diagnostic study Language: Chinese Journal: Journal of Integrative Medicine Year: 2008 Type: Article