Effects of Yiweining recipe on expressions of metalloproteinase-2 and cyclooxygenase-2 mRNAs in ectopic endometrium of rats with endometriosis / 中西医结合学报
Journal of Integrative Medicine
;
(12): 634-8, 2006.
Article
in English
| WPRIM
| ID: wpr-449601
ABSTRACT
OBJECTIVE:
To explore the effects of Yiweining Recipe (YWNR), a compound Chinese herbal medicine, on expressions of metalloproteinase-2 (MMP-2) and cyclooxygenase-2 (COX-2) mRNAs in rats with endometriosis (EM).METHODS:
Operational self-transplantation was applied in establishing the rat models. Detection of MMP-2 and COX-2 mRNAs was conducted with hybridization in situ.RESULTS:
There were significant differences in the expressions of MMP-2 and COX-2 mRNAs between the untreated group and the high-dose YWNR-treated group. YWNR could reduce the expressions of MMP-2 and COX-2 mRNAs.CONCLUSION:
YWNR can treat EM through reducing the positive expressions of MMP-2 and COX-2 mRNAs.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
English
Journal:
Journal of Integrative Medicine
Year:
2006
Type:
Article
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