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Influence of Shenqi Recipe on mesangial cells and interstitial fibroblasts of chronic renal failure rats / 中西医结合学报
Journal of Integrative Medicine ; (12): 122-4, 2003.
Article in Chinese | WPRIM | ID: wpr-449975
ABSTRACT

OBJECTIVE:

To observe the effect of Shenqi Recipe on the proliferation of glomerular mesangial cells (MC) and interstitial fibroblasts (FC) in rats.

METHODS:

The effect of serum containing prepared drugs from normal and chronic renal failure rats treated by Shenqi Recipe on glomerular mesangial cells and intersititial fibroblasts in vitro was observed by MTT colorimetric assay and serophrmacology.

RESULTS:

Compared with the blank sample normal rats, serum containing Shenqi Recipe inhibited the proliferation of MC and FC (P<0.001), and the serum containing Shenqi Recipe of CRF rats had significantly inhibited the proliferation of MC and FC compared with the model group(P<0.001). Conclusion Shenqi Recipe can postpone CRF progress by this mechanism.
Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Journal of Integrative Medicine Year: 2003 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Journal of Integrative Medicine Year: 2003 Type: Article