Effect of baicalin on inflammatory factors and oxygen free radical metabolism in patients with traumatic shock / 中国基层医药
Chinese Journal of Primary Medicine and Pharmacy
;
(12): 1617-1618, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-450624
ABSTRACT
Objective To investigate the effect of baicalin on inflammatory factors and oxygen free radical metabolism in patients with traumatic shock.Methods 38 patients with traumatic shock were treated with baicalin 200mg intravenous injection when admitted to hospital.Before and 1 h after treatment,TNF-α,IL-6,IL-8,MDA and SOD were measured in blood.Results Compared with before treatment,TNF-,IL-6,IL-8,and MDA levels were decreased after treatment (t =7.32,6.12,20.21,16.10,all P < 0.05),while SOD activity was significantly increased (t =1.69,P < 0.01).Conclusion Baicalin could inhibit the production and release of inflammatory factors TNF-α,IL-6,IL-8 in patients with traumatic shock,reduce the damage of oxygen free radicals to the cells.Early treatment with baicalin had protective effect on patients with traumatic shock.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Primary Medicine and Pharmacy
Year:
2014
Type:
Article
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