Allergic Bronchopulmonary Aspergillosis Coupled with Sinusitis in a Nonasthmatic Patient / 결핵및호흡기질환
Tuberculosis and Respiratory Diseases
;
: 278-281, 2011.
Article
in English
| WPRIM
| ID: wpr-45125
ABSTRACT
Allergic bronchopulmonary aspergillosis (ABPA) is a complex clinical entity resulting from an allergic immune response to Aspergillus species, and most often occurs in patients with asthma. ABPA is rarely observed in the absence of asthma, which is, in fact, the principal criterion for its diagnosis. Our patient was a 53-year-old woman with no history of bronchial asthma. She presented with a 1-month history of cough, mucopurulent nasal discharge, and localized pulmonary consolidation. Peripheral blood eosinophilia and elevated serum IgE were observed. Sinus radiography showed right maxillary sinusitis. Pathologic examination of bronchoscopic biopsy specimens revealed conglomerates of fungal hyphae. Pulmonary function and bronchial provocation tests were within normal ranges. The patient was successfully treated for 3 months with itraconazole and oral prednisolone. There has been no evidence of recurrence over a 7-month follow-up. ABPA coupled with sinusitis in a nonasthmatic patient is a very rare occurrence and warrants reporting.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Aspergillosis, Allergic Bronchopulmonary
/
Aspergillus
/
Recurrence
/
Reference Values
/
Asthma
/
Sinusitis
/
Biopsy
/
Bronchial Provocation Tests
/
Immunoglobulin E
/
Prednisolone
Type of study:
Observational study
/
Prognostic study
Limits:
Female
/
Humans
Language:
English
Journal:
Tuberculosis and Respiratory Diseases
Year:
2011
Type:
Article
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