The status of research on estimated glomerular filtration rate and its challenges / 中华检验医学杂志
Chinese Journal of Laboratory Medicine
;
(12): 404-407, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-451272
ABSTRACT
Chronic kidney disease ( CKD ) is a worldwide public health problem.Glomerular filtration rate ( GFR ) is a key indicator for early diagnosis and accurate classification of CKD , how to estimate GFR accurately and conveniently has been a difficulty and hot-points.We describes the development of several major eGFR equations based on creatinine and cystatin C , analysis the impact of the different research methods on performance of equation , and discusses the issue in research and application of eGFR in China.Accordingly make the following recommendations ( 1 ) Expand the study size ( multiple centers) and participants number , then develop and validate eGFR equations based on Chinese population ;(2) Standardize the gold standardof GFR in the study and unify the analysis and evaluation methods;(3) Promote the consistency and standardization of creatinine and cystatin C which is the basis for the wide range of applications of the eGFR formula.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Practice guideline
/
Screening study
Language:
Chinese
Journal:
Chinese Journal of Laboratory Medicine
Year:
2014
Type:
Article
Similar
MEDLINE
...
LILACS
LIS