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The influence of B、T lymphocytes decreased in Apo E gene knockout mice / 中国比较医学杂志
Chinese Journal of Comparative Medicine ; (6): 5-9, 2014.
Article in Chinese | WPRIM | ID: wpr-451318
ABSTRACT
Objective To study the influence of Apo E gene knockout on the lymphocytes . Methods Cells from the peripheral blood, spleen and bone marrow of Apo E knockout and wildtype mice were stained with kinds of antibodies , and analyzed by flow cytometry .Results Compared with wildtype mice , significant differences were found in B and T lymphoctes in the peripheral blood and spleen , but there was no significant difference in pre B cells , T lymphocytes in the thymus and long term hematopoietic stem cell in the Apo E knockout mice .Conclusion Numbers of B lymphocytes decreased in the peripheral blood and spleen , but there was no significant difference in B , T lymphocytes development , and numbers of long term hematopoietic stem cell in Apo E gene knockout mice .

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Comparative Medicine Year: 2014 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Comparative Medicine Year: 2014 Type: Article