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Clinical study on 68 cases with struma ovarii / 中华妇产科杂志
Chinese Journal of Obstetrics and Gynecology ; (12): 451-454, 2014.
Article in Chinese | WPRIM | ID: wpr-452416
ABSTRACT
Objective To study the clinical features,treatment and prognosis of struma ovarii.Methods From January 1990 to January 2012,a total of 68 patients were diagnosed struma ovarii at the Department of Obstetrics and Gynecology,Peking Union Medical College Hospital.Clinical data of these patients were studied retrospectively.Results (1) Characteristics of patientsthe median age of patients was 42 years old (17-81 years).Of those patients,64 cases (94%) were diagnosed begin struma ovarii and 4(6%) were malignant struma ovarii.(2) Clinical feature32(47%,32/68) patients were identified with pelvic mass by ultrasonic test,28 cases(41%) had clinical abdominal pain,8(12%) touched a mass from abdominal wall.Preoperative CA125 were tested in 54 patients,but only 8 cases(15%) had moderate elevation.All patients receive ultrasound examination,and 51 cases (75%) were mulitcystic lesions with many septi,3(4%) solid lesions and 14(21%) solid-cystic tumors.The mean diameter of tumors was(8 ± 3) cm.Ascites was present in 4 (6%,4/68)patients.Sixty-seven patients had unilateral lesions,and 1 patient had bilateral lesions.No patient had hyperthyroidism presentation.Nineteen cases underwent thyroid function test after operation,and the results were normal.(3) Treatmentall patients underwent surgical treatment.Among patients with begin struma ovarii,25 cases underwent cystectomy,15 cases unilateral,2 bilateral salpingo-oophorectomy,22 cases hysterectomy + unilateral or bilateral salpingo-oophorectomy.Four malignant struma ovarii,1 patient underwent fertility-sparing staging surgery,2 patients unilateral salpingo-oophorectomy,1 case hysterectomy + bilateral salpingo-oophorectomy.Two patients received chemotherapy after surgery.(4) Prognosisall patients were followed up in Peking Union Medical College Hospital.The median follow-up time of benign struma ovarii was 5.4 years (6 months-21 years) and there were no recurrence.The median follow-up time of malignant struma ovarii was 11.5 years (9-20 years).Three cases had long-term recurrence at 2,7 and 16 years respectively after surgery.They were received surgical treatment after recurrence and all were alive.Two cases were given by thyroidectomy and 131I treatment.Conclusions Struma ovarii is a rare ovarian monodermal teratoma.Tumorectomy or salpingo-oophorectomy is the appropriate therapeutic treatment for benign struma ovarii.The incidence of malignant struma ovarii is low,and there are no standard treatments.Because of higher long-term recurrence rate,these patients need close follow-up.

Full text: Available Index: WPRIM (Western Pacific) Type of study: Prognostic study Language: Chinese Journal: Chinese Journal of Obstetrics and Gynecology Year: 2014 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Type of study: Prognostic study Language: Chinese Journal: Chinese Journal of Obstetrics and Gynecology Year: 2014 Type: Article