Determination of Pantoprazole Sodium for Injection by High Performance Capillary Electrophoresis / 中国药师
China Pharmacist
;
(12): 240-242, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-452747
ABSTRACT
Objective:
To establish a method for the content determination of pantoprazole sodium for injection by high performance capillary electrophoresis.Methods:
The determination was performed on an uncoated elastic quartz capillary column, the running buff-er was 0. 01 mol·L-1 potassium dihydrogen phosphate buffer, the running voltage was 25kV,the column temperature was 25℃ and the detection wavelength was 289 nm.Results:
The linear range was good within the concentration range of 20. 05-200. 51 μg·ml-1(r=0. 999 6). The average recovery was 99. 03%(RSD=0. 86%, n=9).Conclusion:
The method is simple, sensitive and reproduci-ble, and can be used in the determination of pantoprazole sodium for injection.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacist
Year:
2014
Type:
Article
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