Re port of 51 cases with gastrointestinal stromal tumors / 中国医师杂志

ABSTRACT

Objective To analyze the clinical features and prognostic factors of gastrointestinal stromal tumors. Methods The clinical features and prognostic factors of51 Gastrointestinal Stromal Tumors patients ,who were treated in people`s hospital of xin-jiang ugyur antonomous region from October 1997 to October 2009, were retrospectively analyzed .Results The 1-year, 3-year, 5-year overall survival rates of 51 cases were 85.4%,76.7%,70.7%respectively, a median of 52 months.The 1-year, 3-year, 5-year overall survival rates of the patients with >4 positive lymph nodes were lower than those of patients with ≤4nodes ( P <0.05 ) , The 1-year, 3-year, 5-year overall survival rates of the patients with positive expression of CD 117 were lower than those of patients with negtive CD117( P <0.05).The 1-year, 3-year, 5-yea r overall survival rates of the patients with recurrence and metastasis were low-er than those of patients without ( P <0.05 ) .Conclusions The prognosis of gastrointestinal stromal tumors is related with the posi-tive expression of CD117, recurrence and metastasis .