Cost-effectiveness analysis of three therapeutic schemes for type 2 diabetes mellitus / 重庆医学

ABSTRACT

Objective To compare and analyze of three therapeutic schemes for type 2 diabetes mellitus(T2DM ) using the cost-effectiveness .Methods Using the basic idea of pharmacoeconomics evaluate cost-effect analysis method for three therapeutic schemes(oral glucose-lowering drugs ,oral glucose-lowering drugs + insulin injection one time ,oral glucose-lowering drugs + insu-lin injection twice) .Results The three therapeutic schemes average cost of arrived to 827 .30 yuan/3 months ,1 714 .50 yuan/3 months and 1 087 .50 yuan/3 months ,respectively(P=0 .00);the efficiency of control fasting blood glucose were 56 .51% ,51 .69%and 57 .04% ,respectively (P=0 .754);the efficiency of control 2 h postprandial blood glucose were 50 .56% ,40 .68% and 55 .63% , respectively (P=0 .097);the cost-effectiveness ratio of fasting blood glucose were 14 .64 ,33 .17 and 19 .06 ,respectively ;the cost-ef-fectiveness ratio of 2 h postprandial blood sugar were 16 .36 ,42 .15 and 19 .55 ,respectively .For the oral glucose-lowering drugs group as reference ,the cost-effective ratioscost of control fasting blood glucose and control 2 h postprandial blood glucose were -184 .4 and -89 .8 for oral glucose-lowering drugs + insulin injection one time ,respectively ;the cost-effective ratioscost of control fasting blood glucose and control 2 h postprandial blood glucose were 484 .8 and 51 .26 for oral glucose-lowering drugs + insulin in-jection twice ,respectively .Conclusion According to the principles of economics ,oral medication has the highest cost-effectiveness ratio in the treatment for T 2DM ,and oral medication + insulin injection twice has better therapeutic efficacy .