Relationship between factor-1α and epithelial mesenchymal transformation / 国际肿瘤学杂志
Journal of International Oncology
;
(12): 415-418, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-453378
ABSTRACT
Hypoxia inducible factor (HIF-1α) is a hypoxia response regulator,which is highly expressed in malignant tumors.Researches have shown that HIF-1α plays an important role in epithelial mesenchymal transformation.It can regulate epithelial mesenchymal transition through a series of signal pathways and mechanisms at many levels,to participate in the invasion and metastasis of tumors.To explore the mechanism of HIF-lα controlling epithelial mesenchymal transformation has important significance for the development of new,effective tumor treatment methods.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of International Oncology
Year:
2014
Type:
Article
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