Risk factors of childhood asthma in Wuhan city / 中华实用儿科临床杂志

ABSTRACT

Objective To conform the risk factors of childhood asthma and to provide accordance for the healthy management of children with asthma.Methods A cross-section investigation was carried out by multi-stage random sampling in Wuhan city.The investigation included questionnaire and clinic examination.The study population was the infant and children whose age were 0 to 14 years old,and the sample size was 4 132.One hundren and seventyfour children were diagnosed as asthma,and 173 non-asthma children with similar age in the same region were selected as controls.Chi-square test and multiple Logistic regression analysis were used to screen the risk factors of childhood asthma in Wuhan city.Results Family allergy history,allergic rhinitis,eczema,food allergy and drug allergy were the risk factors of childhood asthma.Furthermore,dust mites,mould,anther dust,mugwort,cat/dog hair were main allergize source.In addition,premature delivery,abdominal delivery,mildew stain in ceiling or floor,raise pets especially cat,chemical fiber pillow and blanket bedclothes will increase the incidence,while spontaneous delivery and breast feeding were with protection effect.The results of multiple Logistic regression analysis showed that children who were with allergic rhinitis,familiar allergic history,dust mites positive test,drug allergy and blanker bedclothes were the high risk group of childhood asthma.Conclusions Childhood asthma is high relative with atopy,and these children who are with allergic rhinitis,familiar allergic history and dust mites positive test should be strictly health management.Chemical fiber pillow,blanket bedclothes,raising pet cats and mould in ceiling and floor in atopy children family should be avoided.