Reference range establishment for healthy children′s ALT and TB test in Panyu district of Guangzhou / 国际检验医学杂志

ABSTRACT

Objective Toinvestigateserumalanineaminotransferase(ALT)andtotalbilirubin(TB)concentrationsofchildrenin Panyu district of Guangzhou ,and establish the reference ranges for ALT and TB tests for healthy children of different gender and different age .Methods 4 065 children were chosen randomly ,and their serum ALT and TB were determined .After excluding the outliers ,the results were analyzed statistically .Results After excluding outliers ,a total of 4 000 children were enrolled in the stud-y ,including 2 241 males ,1 759 females ,aged 2- <9 years old .According to statistical analysis ,reference ranges were established . For male the ALT reference ranges were as follows ,2- <3 years old5 .0-36 .0 U/L ,3- <4 years old7 .0-21 .0 U/L ,4- <8 years old6 .0-21 .0 U/L ,8- <9 years old5 .0-24 .0 U/L ;TB reference ranges of male were as follows ,2- <3 years old3-12μmol/L ,3- <7 years old4-15 μmol/L ,7- <8 years old4-16 μmol/L ,8- <9 years old7-12 μmol/L .ALT reference range of female were as follows ,2- <3 years old6 .0-30 .0 U/L ,3- <4 years old7 .0-22 .0 U/L ,4- <9 years old6 .0-19 .0 U/L ;female TB reference range ,2- <3 years old3 .0-12 .0 μmol/L ,3- <4 years old3 .0-13 .0 μmol/L ,4- <9 years old4 .0-16 . 0 μmol/L .Conclusion Established the reference ranges of ALT and TB test for healthy children in Panyu district .