Correlation between interleukin-10 and T regulatory cells in leprosy patients / 中国免疫学杂志
Chinese Journal of Immunology
;
(12): 1105-1107, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-454848
ABSTRACT
To detect the correlation between Interleukin-10 and CD4+CD25+Foxp3+regulation T cells ( Treg) and to explore the significance and mechanism of them in leprosy patients.Methods:
We used the cytometric bead arra (CBA) to detect the serum Interleukin-10 in 30 leprosy patients and we used flow cytometry to test the Treg cells in 51 leprosy persons.Results:
The con-centration of serum IL-10 in leprosy patients(130.00±54.27)pg/ml was higher than normal people(15.64±7.11)pg/ml,(P<0.05);The percentage of Treg cells in leprosy patients(17.626±8.1977)%was higher than normal people(9.998±1.7062)%,(P<0.05).The relevance between IL-10 and Treg is positive and linear ,( P<0.05 ).Conclusion:
The imbalance between IL-10 and Treg cells may lead to immune abnormal in leprosy patients.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Immunology
Year:
2014
Type:
Article
Similar
MEDLINE
...
LILACS
LIS