A Case of Posttransplant Lymphoproliferative Disease Following Renal Transplantation in a Child
Journal of the Korean Society of Pediatric Nephrology
;
: 245-252, 2003.
Article
in Korean
| WPRIM
| ID: wpr-45532
ABSTRACT
Posttransplant lymphoproliferative disease(PTLD) has emerged as a potential life-threatening complication of immunosuppressive therapy after organ transplantation. The occurrence of PTLD is usually associated with an Epstein-Barr virus(EBV) infection in patients who are treated by aggressive immunosuppressive therapy. PTLD is represented by diverse manifestations ranging from reactive lymphoid hyperplasia to high grade malignant lymphoma. This is a case report of a late PTLD in a child. The patient is a 14-year-old girl, who presented as malignant lymphoma 44 months after successful renal transplantation. There was no evidence of EBV infection. On bone marrow study, many neoplastic lymphoid cells were detected. Aggressive chemotherapy for PTLD had resulted in clinical remission. However the patient expired from uncontrolled sepsis and septic shock after 77 days.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Shock, Septic
/
Bone Marrow
/
Lymphocytes
/
Organ Transplantation
/
Kidney Transplantation
/
Herpesvirus 4, Human
/
Sepsis
/
Pseudolymphoma
/
Transplants
/
Epstein-Barr Virus Infections
Limits:
Adolescent
/
Child
/
Female
/
Humans
Language:
Korean
Journal:
Journal of the Korean Society of Pediatric Nephrology
Year:
2003
Type:
Article
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