The correlation study of diet intervention in 24-hour urinary stone risk factors and recurrence rate of urolithiasis patients in Hengyang area :a reports of analysis of urinary calculi ingredient in 692 patients / 中国医师进修杂志

ABSTRACT

Objective By analyzing the urinary calculi ingredient and 24-hour urinary stone risk factors of urolithiasis patients in Hengyang area,to investigate the effects of diet intervention on recurrence rate in urolithiasis patients,and provide the measures for prevention and treatment.Methods Prospectively collected 692 patients that permanent residents in Hengyang area from September 2008 to September 2012,who had implementation of minimally invasive operation and taken stone specimens to analyze composition,and also collected 24 hours urine to analyze the urinary stone risk factors.They were divided into test group and control group by random number table method,346 cases in each,control group without diet intervention,and test group was given diet intervention according to the stone composition and urinary stonerisk factors.All patients were followed up for 1 year,the urinary stone recurrence rate in Hengyang area was observed.Results Among 692 urolithiasis patients,663 patients completed the study (test group of 341 cases and control group of 322 cases),the expulsion rate was 4.19％(29/692).The 24-hour urinary stone risk factors in control group before and after diet intervention had no significant difference(P ＞ 0.05).In test group after diet intervention,the excretion of ingredients in urine such as dietary calcium (t =3.412,P ＜ 0.05),oxalate(t =3.018,P ＜ 0.05) and uric acid(t =1.990,P ＜ 0.05) was obviously decreased,and urinary citrate (t =3.174,P ＜ 0.05) was increased,but the excretion of ingredients such as magnesium and phosphorus had no significant difference (P ＞ 0.05).After 1 year after diet intervention,the recurrence rate in test group was lower than that in control group [0.88％ (3/341) vs.7.76％ (25/322)],there was significant difference (P ＜ 0.01).Conclusion Diet intervention can effectively reduce the risk of urinary stone according to the stone composition and the 24 hours urine stone risk factors,plays an important role on reducing urinary stone recurrence,which is worth clinical promotion.