Effects of two immunomodulatory agents for vitiligo and cellular immunity / 中华全科医师杂志
Chinese Journal of General Practitioners
;
(6): 684-686, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-455814
ABSTRACT
A total of 107 vitiligo patients were randomly divided into 3 groups.Group A received an intralesional injection of Bacillus Calmette-Guérin-polysaccharide nucleic acid (BCG-PSN) (n =34),group B Compound Glycyrrhizin Tablets (n =36) and group C both (n =37).Before treatment and 3 months after treatment,cellular immune function was detected for each group.Paired comparisons of 3 groups before and after treatment showed that CD4 +,CD4 +/CD8 + ratio increased (all P < 0.05) and CD8 + decreased (P <0.05).After treatment,as compared with groups A and B,CD4 + increases (both P < 0.05) and CD8 + decreased in group C (P <0.05).Group C had an efficiency rate of 91.9% and it was higher than the other two groups (both P < 0.05).An intralesional injection of BCG-PSN plus Compound Glycyrrhizin Tablets could improve immune function and treat vitiligo patients efficiently.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of General Practitioners
Year:
2014
Type:
Article
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