Study on the protecting function of Berberine on the invasion of Streptococcus pneumoniae to A549 cells in vitro / 实用医学杂志
The Journal of Practical Medicine
;
(24): 2538-2539, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-455915
ABSTRACT
Objective To investigate whether Berberine can inhibit the invasion of Streptococcus pueum oniae ( S.pn) to A549 cells in vitro. Methods A549 cells were pretreated with the different concentrations of Berberine and incubated together with S.pn. A549 cells were lysed with 0.025%Triton X-100.Diluted lysate was streaked on TSAB plate and incubated overnight. The colonies on the plate were counted. Results The counts on the plates were 52 ± 21,29 ± 11,13 ± 10,0,0 per well when the concentration of Berberine was 0,25,50,100,200μg/mL, respectively. No invasion was observed when the concentration of Berberine was 100 μg/mL. Conclusion Berberine can inhibit the invasion of S.pn to A549 cells in dose-dependent maner in vitro.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
The Journal of Practical Medicine
Year:
2014
Type:
Article
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